Protecting the heart 28 September 2018 Heart disease is one of the leading health issues faced by people with diabetes. However, researchers believe that high density lipoproteins (HDL), sometimes referred to as good cholesterol, could help protect the heart. Dr Joanne Tan from the South Australian Health and Medical Research Institute is looking at whether HDL can help with angiogenesis, the process of forming new blood vessels from pre-existing blood vessels. 鈥淒iabetes can lead to impaired angiogenesis. That means the body鈥檚 capacity to create new blood vessels, and increase blood supply, is not working as it should,鈥 Dr Tan said. 鈥淲e鈥檝e previously shown that HDL can help repair impaired angiogenesis now we are trying to understand how that happens. 鈥淭hanks to the grant from 黑料网 we will be investigating whether miRNAs, small molecules involved in the signaling process, affects how HDL helps the body respond to impaired angiogenesis. 鈥淲e hope this could lead to a new gene therapy which may help reduce the risk of heart disease in some people with diabetes.鈥
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